TL;DR

Orchestration frameworks like LangChain, LlamaIndex, and Haystack simplify building complex AI workflows by providing abstractions for common patterns like retrieval, chaining, and agent behaviors. Each has different strengths: LangChain for general-purpose chains and agents, LlamaIndex for document indexing and RAG, Haystack for production search pipelines. Start with custom code for simple use cases, adopt frameworks when complexity grows, and avoid over-abstraction by understanding what's happening under the hood.

What Orchestration Frameworks Do

Building AI applications involves more than calling openai.ChatCompletion.create(). Real systems need to:

  • Chain multiple LLM calls together with context flow
  • Retrieve relevant documents before generating answers (RAG)
  • Parse outputs and call external tools based on model decisions
  • Manage conversation memory across turns
  • Handle errors, retries, and rate limits
  • Log and monitor complex workflows

Orchestration frameworks abstract these patterns into reusable components. They save you from reinventing common patterns, but add dependencies and learning curves. The key question is whether the abstraction helps or hinders your specific use case.

The Major Players

LangChain: The Swiss Army Knife

LangChain is the most popular general-purpose orchestration framework. It provides abstractions for chains (sequential operations), agents (LLMs that choose actions), memory systems, document loaders, and tool integration.

Simple chain example:

from langchain.chat_models import ChatOpenAI
from langchain.prompts import ChatPromptTemplate
from langchain.schema.output_parser import StrOutputParser

# Create a chain: prompt -> model -> parse output
prompt = ChatPromptTemplate.from_template("Translate {text} to {language}")
model = ChatOpenAI(model="gpt-4")
chain = prompt | model | StrOutputParser()

# Run it
result = chain.invoke({"text": "Hello world", "language": "Spanish"})
# Output: "Hola mundo"

RAG example:

from langchain.embeddings import OpenAIEmbeddings
from langchain.vectorstores import FAISS
from langchain.text_splitter import RecursiveCharacterTextSplitter
from langchain.chains import RetrievalQA

# Load and chunk documents
splitter = RecursiveCharacterTextSplitter(chunk_size=1000)
chunks = splitter.split_documents(documents)

# Create vector store
embeddings = OpenAIEmbeddings()
vectorstore = FAISS.from_documents(chunks, embeddings)

# Create QA chain
qa = RetrievalQA.from_chain_type(
    llm=ChatOpenAI(),
    retriever=vectorstore.as_retriever(),
    return_source_documents=True
)

answer = qa({"query": "What are the main findings?"})

Pros:

  • Extremely comprehensive - covers most use cases
  • Large ecosystem of integrations (100+ LLM providers, vector stores, tools)
  • Active community and frequent updates
  • Good for rapid prototyping

Cons:

  • Complex API with frequent breaking changes
  • Heavy abstraction can obscure what's happening
  • Performance overhead from generic abstractions
  • Difficult to debug when things go wrong
  • Documentation quality varies

Best for: Rapid prototyping, teams exploring multiple approaches, projects needing many integrations.

LlamaIndex: Built for RAG

LlamaIndex (formerly GPT Index) specializes in indexing and querying over documents. It excels at loading data from various sources, creating efficient indexes, and powering question-answering systems.

Basic RAG example:

from llama_index import VectorStoreIndex, SimpleDirectoryReader
from llama_index.llms import OpenAI

# Load documents
documents = SimpleDirectoryReader("./data").load_data()

# Create index
index = VectorStoreIndex.from_documents(documents)

# Query
query_engine = index.as_query_engine(llm=OpenAI(model="gpt-4"))
response = query_engine.query("Summarize the key points")

print(response.response)
print(response.source_nodes)  # See which chunks were used

Advanced indexing:

from llama_index import TreeIndex, KeywordTableIndex
from llama_index.composability import ComposableGraph

# Create multiple indexes for different query types
vector_index = VectorStoreIndex.from_documents(docs)
tree_index = TreeIndex.from_documents(docs)
keyword_index = KeywordTableIndex.from_documents(docs)

# Compose them
graph = ComposableGraph.from_indices(
    TreeIndex,
    [vector_index, tree_index, keyword_index],
    index_summaries=["semantic search", "hierarchical", "keywords"]
)

query_engine = graph.as_query_engine()
response = query_engine.query("Complex question requiring multiple strategies")

Pros:

  • Laser-focused on document indexing and retrieval
  • Cleaner, more stable API than LangChain
  • Excellent data connectors (databases, APIs, file formats)
  • Built-in observability for understanding retrieval
  • More opinionated = fewer decisions

Cons:

  • Less flexible for non-RAG use cases
  • Smaller ecosystem than LangChain
  • Less suitable for agent-based workflows
  • Fewer tool integrations

Best for: Document QA systems, knowledge bases, semantic search applications, teams focused on retrieval quality.

Haystack: Production-Grade Pipelines

Haystack, developed by deepset, emphasizes production-ready search and NLP pipelines. It's more opinionated about architecture and includes strong support for hybrid search and deployment.

RAG pipeline example:

from haystack import Pipeline
from haystack.nodes import EmbeddingRetriever, PromptNode, PromptTemplate
from haystack.document_stores import FAISSDocumentStore

# Setup document store
document_store = FAISSDocumentStore(embedding_dim=1536)
document_store.write_documents(documents)

# Create retriever
retriever = EmbeddingRetriever(
    document_store=document_store,
    embedding_model="text-embedding-ada-002",
    model_format="openai"
)
document_store.update_embeddings(retriever)

# Create prompt
template = PromptTemplate(
    prompt="Given the context: {join(documents)}\n\nAnswer: {query}",
    output_parser={"type": "AnswerParser"}
)

prompt_node = PromptNode(
    model_name_or_path="gpt-4",
    default_prompt_template=template
)

# Build pipeline
pipeline = Pipeline()
pipeline.add_node(component=retriever, name="Retriever", inputs=["Query"])
pipeline.add_node(component=prompt_node, name="PromptNode", inputs=["Retriever"])

# Run
result = pipeline.run(query="What are the findings?")

Pros:

  • Designed for production from the ground up
  • Strong support for hybrid search (keyword + semantic)
  • Built-in evaluation and benchmarking tools
  • RESTful API for deployment
  • Clear pipeline abstraction

Cons:

  • Steeper learning curve
  • More rigid structure
  • Smaller community than LangChain/LlamaIndex
  • Less suitable for rapid experimentation

Best for: Production deployments, enterprise search systems, teams prioritizing stability and monitoring.

Custom Code: The Control Option

Sometimes the best framework is no framework. Simple use cases often don't justify the complexity.

Simple RAG without frameworks:

import openai
from sentence_transformers import SentenceTransformer
import numpy as np

# Setup
model = SentenceTransformer('all-MiniLM-L6-v2')

def retrieve(query, documents, top_k=3):
    # Embed query and documents
    query_emb = model.encode([query])
    doc_embs = model.encode(documents)

    # Cosine similarity
    scores = np.dot(query_emb, doc_embs.T)[0]
    top_indices = np.argsort(scores)[-top_k:][::-1]

    return [documents[i] for i in top_indices]

def answer_question(query, documents):
    # Retrieve relevant context
    context = retrieve(query, documents)

    # Generate answer
    prompt = f"Context: {' '.join(context)}\n\nQuestion: {query}\nAnswer:"

    response = openai.ChatCompletion.create(
        model="gpt-4",
        messages=[{"role": "user", "content": prompt}]
    )

    return response.choices[0].message.content

# Use it
docs = ["Python is a programming language.", "Python was created by Guido van Rossum."]
answer = answer_question("Who created Python?", docs)

Pros:

  • Complete control and transparency
  • No external dependencies
  • Easy to debug and modify
  • No framework learning curve
  • Better performance (no abstraction overhead)

Cons:

  • Need to implement everything yourself
  • Risk of bugs in custom code
  • Must stay current with best practices
  • Harder to onboard new team members

Best for: Simple use cases, teams with strong engineering skills, performance-critical applications, projects with unique requirements.

Comparison Framework

Criterion LangChain LlamaIndex Haystack Custom
Learning Curve Steep Moderate Steep None
Flexibility High Medium Medium Maximum
RAG Quality Good Excellent Excellent Depends
Agent Support Excellent Limited Limited DIY
Production Ready Requires work Moderate Excellent Depends
Community Largest Large Medium N/A
Stability Frequent changes More stable Very stable You control
Best Use Case Exploration Document QA Enterprise search Simple/unique

Decision Framework

Use LangChain if:

  • You're exploring multiple approaches rapidly
  • You need agent capabilities (tool use, reasoning loops)
  • You want maximum ecosystem integration
  • You have time to deal with API changes

Use LlamaIndex if:

  • Your primary use case is RAG/document QA
  • You want a focused, stable API
  • Retrieval quality is your top priority
  • You need strong data connector support

Use Haystack if:

  • You're building production search systems
  • You need hybrid search (keyword + semantic)
  • Evaluation and monitoring are critical
  • You want RESTful deployment built-in

Use custom code if:

  • Your use case is simple (single LLM call, basic retrieval)
  • You have specific performance requirements
  • Your team has strong engineering capabilities
  • You need complete control and transparency

Common Pitfalls

Over-abstraction: Frameworks can hide what's actually happening. When debugging, you're fighting both your code and the framework's abstractions. Start simple and add complexity only when needed.

Framework lock-in: Deep integration with a framework makes switching costly. Keep your business logic separate from framework-specific code.

Version churn: LangChain especially moves fast with breaking changes. Pin versions and test thoroughly before upgrading.

Performance overhead: Generic abstractions have costs. For high-throughput systems, measure whether framework overhead is acceptable.

Debugging difficulty: Stack traces through framework code are painful. Invest in good logging and understand the framework's execution model.

Practical Recommendations

  1. Start small: Begin with custom code or the simplest framework approach. Add abstraction when complexity justifies it.

  2. Understand the basics: Learn how embeddings, vector search, and prompt engineering work before adopting frameworks. This makes debugging possible.

  3. Keep it modular: Separate your business logic from framework code. Use dependency injection so you can swap implementations.

  4. Monitor everything: Frameworks make it easy to build complex systems. Make sure you can observe what's happening in production.

  5. Test without the framework: Write integration tests that verify behavior without relying on framework internals. This protects against breaking changes.

  6. Read the source: When documentation fails or bugs appear, framework source code is your friend. It's often clearer than the docs.

The Bottom Line

Orchestration frameworks solve real problems, but they're not magic. LangChain offers breadth, LlamaIndex offers RAG excellence, Haystack offers production maturity. Custom code offers control.

The right choice depends on your use case complexity, team skills, and time constraints. Start with the simplest thing that works, measure carefully, and add abstraction only when the benefit is clear. The best framework is the one that disappears into the background and lets you focus on building value for users.